Three-Dimensional Landscape of Genome. HIPMap (high-throughput imaging position mapping) accurately determines the position of a gene in the three-dimensional (3D) space of the cell nucleus. In this illustration, images of genes (red, green, and blue spots within the nuclei of HeLa cells) are artificially superimposed on images of multi-well plates. Creator: Tom Misteli, Sigal Shachar, Murali Palangat.
Credit: National Cancer Institute (NCI)